We carry out computations aimed at understanding the reactivity of bicyclobutanes and related strained species.

Kraemer, Y.; Buldt, J. A.; Stephens, A. M.; Kong, W.-K.; Ragan, A. N.; Haidar, Z. C.; Patel, A. H.; Fettinger, J. C.; Tantillo, D. J.; Pitts, C. R. Angew. Chem. Int. Ed. 2024, 63, e202319930: "Overcoming a Radical Polarity Mismatch in Strain-Release Pentafluorosulfanylation of [1.1.0]Bicyclobutanes: An Entryway to Sulfone- and Carbonyl-Containing SF5–Cyclobutanes"

Park, Y. S.; Wang, S. C.; Tantillo, D. J.; Little, R. D. J. Org. Chem. 2007, 72, 4351-4357: "A Highly Selective Rearrangement of a Housane-derived Cation Radical; an Electrochemically Mediated Transformation"

Gerkin, J. B.; Wang, S. C.; Preciado, A. B.; Park, Y. S.; Nishiguchi, G.; Tantillo, D. J.; Little, R. D. J. Org. Chem. 2005, 70, 4598-4608: "Remote Substituent Effects upon the Rearrangements of Housane Cation Radicals"


back to list of research projects